G6PD and G6PD deficiency: The G6PD c.202T allele is associated with such a mild phenotype that even hemizygous boys and homozygous girls retain 12% of normal G6PD activity5, 34 and, as a result, are rarely affected by the more severe manifestations of G6PD deficiency, with the exception of challenge by powerful oxidants such as dapsone.35