The TUNEL-positive cell number in H89 and α-MSH-treated dry eye group was even greater than PD98059 and α-MSH-treated dry eye group, while the difference was not significant (Fig. 5B, D+H89+α-MSH vs D+PD+α-MSH, p = 0.141). Here, STAMBP is linked to Keratoconjunctivitis sicca.