GNPAT and rhizomelic chondrodysplasia punctata: Deficiencies in the peroxisomally localized ether lipid biosynthetic activities of glyceronephosphate O-acyltransferase (GNPAT) and alkylglycerone phosphate synthetase (AGPS) cause the human disease, rhizomelic chondrodysplasia punctata (RCDP).