In addition, IHC staining revealed that high B56γ was detected in 8 (40%) of 20 specimens with high nuclear p27 expression, but it was only detected in 2 (7%) of the 27 specimens with low nuclear p27 expression in non-tumor parts of colon cancer specimens (Figure 8A and 8C, lower panel). This evidence concerns the gene CDKN1B and malignant colon neoplasm.