The results indicated that CARgpc3 T cells could efficiently lyse NCI-H520-GPC3 and SK-MES-1-GPC3 cells but not the parental cell lines (Figure 4A–4D), whereas the control T cells (mock and 2D3–28BBZ) could not initiate the specific lysis of these tumor cells. The gene discussed is GPC3; the disease is neoplasm.