GPC3 and neoplasm: In sections with a high level of GPC3 expression (14 out of 19), GPC3 seemed to be relatively homogeneously expressed in LSCC tissues with a mean rate of GPC3- positive tumor cells equal to 80.79%, which is significantly higher than that in the low-expression group (5 out of 19) in which only 31.18% of cells were GPC3-positive (P < 0.001) (Figure 1D–1E).