MKI67 and metastatic malignant neoplasm in the lymph nodes: The expression levels of miRNA-196a were elevated in patients with pathological stage pT3 or higher (P = 0.004), lymph node metastasis (P = 0.080), American Joint Committee on Cancer stage II or higher (P = 0.002), high mitotic index (≥2 per 10 high-power fields [HPFs]) (P = 0.012), high Ki-67 labeling index (≥3%) (P = 0.108), and recurrence (P = 0.011) (Table 2, Fig. 2).