BAP1 and Miyoshi myopathy: Although MM tumor tissues were not available for MARF2-IV-2 and MARF40-III-1, IHC of MARF2-IV-2 giant bone tumor tissue indicated lack of BAP1 nuclear staining (S2 Fig), supporting presence of LOH, as our previous studies have shown a 100% correlation between LOH and lack of nuclear staining [26].