Comparison of cell surface marker expression on myeloid cells isolated from the lungs of WT and SHIP−/− 4T1 tumor-bearing mice revealed that WT CD11b+Gr1+ cells expressed higher levels of Gr1 than SHIP−/− CD11b+Gr1+ cells (Supplemental Fig. 3A), while SHIP−/− Mφs exhibited higher expression of F4/80 (Supplemental Fig. 3B). The gene discussed is INPP5D; the disease is neoplasm.