TP53 and malignant colon neoplasm: For example, in two large studies from Korea and China, Pro/Pro at p53 codon 72 (rs1042522) was found to be associated with colon cancer; the respective frequencies of the Pro allele in cases and controls were 34.0% and 36.4% in Koreans and 50.3% and 39.6% in Chinese [32].