Nevertheless, exhaustive search of the literatures failed to find any study that examined the haplotype association with T2DM, making the present study the first to report this haplotype association. AGT rs699-C allele was previously found to be associated with increased risk of T2DM in the Pakistani [15], despite no significant association in the Chinese [16] and recently the Japanese [17]. Here, AGT is linked to type 2 diabetes mellitus.