IFNB1 and asthma: Whether the low IP-10 production in the current study might be related to deficiencies in other type of IFN (for example, IFN-λ) warrants further investigated as there is evidence that IFN-λ can induce IP-10 production.34 Bafilomycin inhibited HRV-induced IFN-α, IFN-β and IP-10 production in those with asthma (Figure 6), similar to the results seen in healthy subjects (Figure 4), suggesting that there is no gross deficit in endosomal function in asthma.