HMGB3 and neoplasm: Other proteins upregulated by chlamydia in the reproductive system that contribute to EMT, fibrosis, oncogenesis and tumor progression, invasiveness and metastasis are BAG6 (also called BAT3) [32], the HMGB3 protein [33,34], Svil [35,36], Smu1 [37], the oncogene Lsm1 [38,39], FXR1 [40], PSMD14 and PSMB5 [41], Cops2 or CSN2, [42–44], Actr1a [45], Txn2 or Trx2 [46], Dpm3 [47], and FABP3 [48].