SERPINH1 and cervical intraepithelial neoplasia: In addition, members of miR-29 family control cell invasion by targeting for suppression molecules that are involved in cell invasion and migration in the focal adhesion signaling pathway [22]; furthermore, miR-29a targets the heat-shock protein-47 (HSP47), a member of the serpin superfamily of serine proteinase inhibitors and a molecular chaperone involved in the maturation of collagen molecules; HSP47 is upregulated in fibrosis and several cancers especially cervical intraepithelial neoplasia where miR-29a is often down-regulated [23].