EPHA3 and neoplasm: In addition to the above potentially oncogenic fusions, gene members of the axon guidance pathway, recurrently altered in pancreatic cancer [25], were also found to be involved in multiple fusions: CADM2-EPHA3 fusion in the tumor’s genome, fusion of chromosome 19 to SLIT1 on chromosome 10 in the THJ-21T genome and SRGAP3-SETD5 fusion in THJ-29T (Additional file 1).