IL10 and infection: The role of connective tissue mast cells following repeated infection was investigated using mast cell‐deficient Mctp5Cre iDTR mice 26, 27, and we found that the absence of mast cells in the skin of 4x infected mice resulted in a reduction in the production of immunoregulatory IL‐10 by in vitro cultured skin biopsies, an increase in the number of MHC–II+ cells in the skin and led to a small but significant increase in the proliferation of cells recovered from the sdLN.