The increase in the number of infiltrating MHC‐IIhi DC in the skin infection site in the absence of eosinophils (following anti‐CCR3 mAb treatment, and in eosinophil‐deficient ΔdblGATA‐1 mice) could enhance downstream antigen presentation to naïve T cells and therefore increase the responsiveness of CD4+ T cells in the sdLN. This evidence concerns the gene CCR3 and skin infection.