SLC2A1 and Hyperglycemia: In contrast, data from experimental studies in rats show a significant reduction in FDG uptake in the lesions of infectious and noninfectious inflammatory models with moderate hyperglycaemia (150 – 180 mg/dl, 8.3 – 10.0 mmol/l) but also, after glucose loading, decreased GLUT-1 and GLUT-3 expression in infectious lesions [27, 28].