Interestingly, the increased killing of NK cells in coculture with IL-15 EP DC or IL-15/IL-15Rα EP DC could also be shown using DC and NK cells derived from a glioblastoma multiforme patient pointing towards a more general immunostimulatory approach that could be applied to both hematological and solid tumors (Supplemental Figure 3). The gene discussed is IL15; the disease is glioblastoma.