Significant positive associations between alcohol and both PR+ and PR- breast cancer were found in overall and in postmenopausal women, with no evidence of heterogeneity in the association comparing PR+ and PR- breast cancer (P > 0.05), but with a suggestion of an interaction between menopausal status and alcohol intake for PR+ breast cancer (P = 0.05) (Table 3). The gene discussed is PGR; the disease is breast cancer.