RHOC and hepatocellular carcinoma: Upregulated expression of RhoC is related to the metastasis and invasiveness of many kinds of human malignant tumors, such as non-small cell lung carcinoma and hepatocellular carcinoma cells [26–37] and is correlated with a poorer prognosis in patients with pancreatic adenocarcinoma and ovarian carcinoma [38–41].