A meta-analysis of 10 studies that looked at a single value for serum CRP to be used as a cutoff for bacterial disease, including both gram-positive and gram-negative bacteria, resulted in a bimodal outcome, with three studies recommending that the CRP cutoff value be set between 6 and 20 mg/L and seven studies recommending a cutoff of 60–100 mg/L (19). The gene discussed is CRP; the disease is bacterial infectious disease.