PTEN deletions were found in 19 % of NST cancers, 9 % of lobular (p = 0.0036 vs NST), 35 % of papillary cancers (p = 0.1150 vs NST) and 46 % of cancers with medullary features (p = 0.0002 vs NST). The gene discussed is PTEN; the disease is cancer.