Furthermore, a histological analysis of the ocular tissue affected by T. gondii is necessary as well as investigations of the cytotoxicity of NK and CD8+ T cells to clarify the expression of MICA molecules and to gain a better understanding of the role of cells expressing the NKG2D receptor in the immunopathogenesis of ocular toxoplasmosis. The gene discussed is MICA; the disease is ocular toxoplasmosis.