In 2004 in a study performed on two cancer cell lines (one derived from cervical squamous carcinoma, the other one from a metastatic site of cervical carcinoma), Favia et al. [47] have analyzed the interaction occurring between HPV type 16 E7 mRNA and the intermediate cytokeratin filaments 7 and 19 and reported data in favor of a possible association between HPV16 E7 protein level and CK19. The gene discussed is KRT19; the disease is cervical carcinoma.