IGFBP3 and neoplasm: Similarly, after IR, tumors formed from TE-1-Ad-IGFBP-3-Lus2 cells (from a mean tumor volume of 200 mm3 to 250 ± 30.7 mm3, before and after the same treatment) implanted in nude mice grew more slowly a than those formed by the control (from a mean tumor volume of 200 mm3 to 550 ± 49.7 mm3, before and after the same treatment, P < 0.05, Fig. 4A,C).