KRAS and non-small cell lung carcinoma: A second larger study looking at 204 patients with advanced non-squamous NSCLC that included 77 patients with KRAS mutant phenotype who had a significant inferior outcome with respect to disease response rate (0.04), disease control rate (0.05) and progression-free survival (p = 0.05) in patients being treated with first-line platinum-based chemotherapy regimens when compared to patients conferring KRAS wild-type and EGFR wild-type mutations [22].