Neither CD8+ nor CD4+ T-cell depletion affected liver-stage burden in Ad-M CS-vaccinated mice compared to the control (Fig. 3Ai), and there was a strong correlation between the endpoint CSP Ab titer and the time to 1% blood-stage infection (Fig. 3Bi), suggesting that antibodies help mediate protection in this Ad-M CS regimen. Here, CD8A is linked to infection.