TF and chronic thromboembolic pulmonary hypertension: Moreover, in the CTEPH and PTE groups, TF antigen levels significantly correlated with monocyte TF mRNA levels (r = 0.83, P < 0.01; r = 0.91, P < 0.01), suggesting monocyte TF may play a key role in CTEPH thrombosis and remodeling of the pulmonary vasculature (Fig. 4).