Meanwhile, in the 89 patients with lymph node metastasis, 53 patients co-expressed CCR7 and MUC1 (59.6 %), seven patients only expressed CCR7 (13.2 %), 18 patients only expressed MUC1 (20.2 %), and 11 patients did not express CCR8 or MUC1 (12.4 %). The gene discussed is CCR7; the disease is metastatic malignant neoplasm in the lymph nodes.