Interestingly, our observations are in line with recent findings suggesting that a subpopulation of TAMs, defined as CD206+/TIE2Hi/CXCR4Hi, accumulate around blood vessels after chemotherapy in breast cancer, where they promote tumor revascularization and relapse, partly by release of VEGF (Hughes et al, 2015). The gene discussed is MRC1; the disease is breast carcinoma.