CDKN2B and coronary artery disorder: The risk allele at the well-known coronary heart disease (CHD) locus, CDKN2A/CDKN2B in 9p21, has been shown to be associated also with IS (2), and a recent genome-wide analysis using data from METASTROKE, Coronary Artery Disease Genome-wide Replication and Meta-analysis (CARDIoGRAM), and Coronary Artery Disease (C4D) Genetics consortia reported 15 loci at genome-wide significant association with both IS and CHD in a joint analysis (3).