Anti-CD49d pretreatment efficiently and preferentially blocked transendothelial (p < 0.001) and fibronectin-driven migration of CD49dhiCD4+ (p < 0.05) and CD49dhiCD8+ (p < 0.01) T cells isolated from DMD patients (Fig. 4a, b). The gene discussed is FN1; the disease is Duchenne muscular dystrophy.