As presented in Figure 5, the expressions of p-PI3K, p-Akt, p-NF-κBp65, and p-IκBα were upregulated in diabetes mice, taking the expressions of PI3K, Akt, NF-κBp65, and IκBα as inner controls, respectively, (P < 0.01). Here, AKT1 is linked to diabetes mellitus.