At least 13 loci and 9 genes are associated with both autosomal dominant (PARK1 and PARK4/α-Synuclein; PARK5/UCHL1; PARK8/LRRK2; PARK11/GIGYF2; PARK13/Omi/Htra2) and autosomal recessive (PARK2/Parkin; PARK6/PINK1; PARK7/DJ-1; PARK9/ATP13A2) PD [67]. The gene discussed is LRRK2; the disease is Parkinson disease.