NOX1, NOX3, and NOX5 expression suggested minor changes in thyroid cancers (Fig. 1a, c, e), whereas the expression of NOX2 and NOX4 showed increased mRNA synthesis in papillary thyroid and anaplastic thyroid cancers (Fig. 1b, d). The gene discussed is CYBB; the disease is thyroid gland undifferentiated (anaplastic) carcinoma.