In contrast, Reiman et al. [20] conducted a meta-analysis considering the prognostic and predictive value of TUBB3 in resected NSCLC patients enrolled in four randomized controlled trials of adjuvant chemotherapy, showing a prognostic effect of high TUBB3 expression while they were unable to demonstrate its predictive role in adjuvant setting. Here, TUBB3 is linked to non-small cell lung carcinoma.