RAPGEF1 and infection: It is interesting to note that while the activation of the cytokines, such as IL4_T, IL5_T, IL6_T, and the receptors, IL12R_T [52] and IL1R_T [55], show fluctuations with respect to the control (uninfected scenario), certain other molecules, such as RAP1_T, P19_T, C3G_T, CRKL_T, TYK2_T, and SOC3_T, are distinctly upregulated as a result of the infection.