2011). Another study has shown that prenatal hypoxia exposure can damage the hepatic parenchymal cells associated with hepatic insulin signaling, resulting in altered hepatic development, insulin sensitivity, and glucose metabolism in postnatal life (Cao et al. 2012). Recent studies in rats have shown that perinatal IH exposure can result in oxidative stress, causing a permanent immune response subsequently resulting in features of diabetes mellitus (Pae et al. 2013). This evidence concerns the gene INS and diabetes mellitus.