CRP and rheumatoid arthritis: The CCP-positive subset of patients with RA is linked with a more severe disease development and worse prognosis.5, 7, 8 However, no association of specific ACPAs with clinical parameters has been described so far.56 Here, we found that cTNC5 antibodies do not correlate with a number of clinical parameters, however, there was a significant association of cTNC5 antibodies with disease activity (DAS28-CRP), suggesting that cTNC5 antibodies may be a useful tool for predicting clinical outcome.