Phagocytosis of apoptotic cells by macrophages and DCs can inhibit their production of proinflammatory mediators while leading to the production of TGF-β and to the generation of regulatory T cells.3, 4, 5 Under steady-state conditions, the capture of apoptotic cells by DCs is thought to contribute to the maintenance of peripheral tolerance.6 In infection-driven inflammatory settings, the ingestion of apoptotic cells by macrophages and DCs may be exploited by pathogens to promote infection by inhibiting components of the antimicrobial response. The gene discussed is TGFB1; the disease is infection.