We chose to focus on VEGF as our primary tissue marker as it has been shown to be an important regulator of endometrium-embryo crosstalk and neoangiogenesis around the time of implantation [51,52]; it may have reduced expression in women with endometrial dysfunction and otherwise unexplained infertility [53]; and its expression is reduced by anhydrous ethanol injury modeling in rodents [37]. The gene discussed is VEGFA; the disease is Infertility.