These results are similar to those reported by Wang et al. [7] who studied the Chinese Han population, but differ from those stated by Hu et al. [23] who found that PLCE1 mRNA expression level is lower in ESCC than that in normal tissues; nevertheless, no significant difference was observed in the IHC score between ESCC and normal match. This evidence concerns the gene PLCE1 and esophageal squamous cell carcinoma.