The following 19 clinicopathological factors analyzed in the training cohort were as follows: age, gender, HBsAg, hepatitis C virus antibody (HCV-Ab), AFP, ALT, γ-GT, liver cirrhosis, Child-Pugh score, tumor differentiation, tumor size, tumor number, tumor encapsulation, vascular invasion, BCLC stage, miR-145, miR-31, miR-92a, and miR-10b. The gene discussed is AFP; the disease is cirrhosis of liver.