BCL2L1 and lymphoma: To test whether up-regulation of BCL2 and BCL-XL might cause lymphoma cells to become especially dependent on these pathways for survival in the absence of BCL6, we knocked down BCL6 in OCI-Ly1 cells as before and treated with the BCL2 and BCL-XL inhibitor ABT-737 250 nM for 72 h.