Since CDC42EPs and septins, as with GLAST, are implicated in human neurological and psychiatric disorders including schizophrenia by unbiased proteomic and genome-wide association studies8, 9, 40, 41, 42, 43, whether relevant mechanisms underlie the pathophysiology in other brain regions is to be tested in future studies. Here, SLC1A3 is linked to schizophrenia.