BAX and neoplasm: After adjusting for age, gender, ECOG PS, histology, tumor stage, smoking status, chemotherapy regimens, weight loss, BCL2-938C>A, and BAX-248G>A, the logistic regression model analysis showed that the following parameters were able to predict the treatment response: ECOG PS (adjusted OR 2.112, 95% CI 1.156–3.857, p = 0.015), tumor stage (adjusted OR 2.887, 95% CI 1.510–5.518, p = 0.001), smoking status (adjusted OR 2.446, 95% CI 1.140–5.247, p = 0.022) and BAX-248G>A (GG vs. GA, adjusted OR 1.943, 95% CI 1.035–3.648, p = 0.039; GG vs. GA+AA, adjusted OR 1.867, 95% CI 1.035–3.369, p = 0.038).