However, other factors, such as age, sex, infection time, etiology, HbsAg, hepatitis B virus copies, alanine aminotransferase (ALT), aspartate aminotransferase, total bilirubin, prothrombin time, and AFP were all detected to have none apparent influence regarding serum Hs-CRP level (all P > 0.05). The gene discussed is AFP; the disease is infection.