Three representative examples of windowed nucleobase affinity and mRNA codon content profiles for human proteins are shown: WOX-1, a putative oxidoreductase protein, showed average matching (r = +0.70; Fig. 4B), ING5, a p53 interacting protein implicated in tumor suppression, showed greater than average matching (r = +0.90; Fig. 4C) and DUSP7, a phosphatase involved in the mitogen-activated protein kinase cascade, showed no apparent matching (r = +0.04; Fig. 4D). The gene discussed is ING5; the disease is neoplasm.