TRPV1 and neoplasm: Daphane-type diterpenoids showed various biological effects including anti-cancer, transient receptor potential cation channel subfamily V member 1 (TRPV1) activating, anti-fertility, pesticide, neurotrophic, cholesterol-lowering, anti-hyperglycemic, irritant, tumor-promoting, and anti-human immunodeficiency virus (HIV) activities [6].