VIM and cancer: To verify the effect of the combination of NTP with cetuximab on invasive cellular phenotypes at the molecular level, we analyzed protein levels of Slug and Snail, which are transcription factors and master regulators of the epithelial-to-mesenchymal transition (EMT); as well as E-cadherin or vimentin, which are cellular machinery associated with the invasive phenotype of cancer cells and thus hallmarks of the EMT20, 21.