We found that there were five common FFLs altered in both subtypes of NSCLC, involving E2F1_hsa-miR-195-5p_CCNE1, E2F1_hsa-let-7a-5p_AURKB, E2F1_hsa-miR-92a-3p_BCL2L11, EGR1_hsa-miR-30a-5p_GNAQ and SPI1_hsa-miR-146a-5p_TLR4. This evidence concerns the gene TLR4 and non-small cell lung carcinoma.