No lung phenotype has been described in Akt2−/− mice and although RNA-seq was not performed on non-tumor bearing Akt2−/− lung tissue we did find a non-significant, 2.6-fold increase in Sftpc expression (a marker of type II alveolar cells) in SPC-IGFIR-Akt2−/− tumors compared to SPC-IGFIR tumors. The gene discussed is IGF1R; the disease is neoplasm.